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Differential B-cell receptor signaling requirement for adhesion of mantle cell lymphoma cells to stromal cells

2020-03-09

Abstract excerpt

Interactions between lymphoma cells and stromal cells play a key role in promoting tumor survival and development of drug resistance. We identified differences in key signaling pathways between the JeKo-1 and REC-1 mantle cell lymphoma (MCL) cell lines, which exhibited different patterns of stromal cell adhesion and chemotactic migration towards stroma-conditioned medium. The identified adhesion-regulated genes re...

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Identifiers and source

Literature Corpus work
0d990954-195d-54f0-89c5-9e9d2eab594f
DOI
10.1101/2020.03.06.980235
Open publication

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Differential B-cell receptor signaling requirement for adhesion of mantle cell lymphoma cells to stromal cellsDOI 10.1101/2020.03.06.980235
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