Article
Transcriptional profiling and assessment of cell lines as in vitro models for mantle cell lymphoma.
Leukemia research - 1 Feb 2005
Ek Sara, Ortega Eva, Borrebaeck Carl A K
Abstract excerpt
Mantle cell lymphoma (MCL) is an aggressive malignancy and new treatment modalities must be established to increase patient survival time. In the search for new therapeutic targets, reliable and well-characterised in vitro models are essential. In this study, we have characterised three MCL cell lines (SP53, Granta 519 and NCEB1) in comparison with primary tumours from MCL, follicular lymphomas (FL), a FL cell...
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