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MULTIPLE, REDUNDANT CARBOXYLIC ACID TRANSPORTERS SUPPORT MITOCHONDRIAL METABOLISM IN <i>PLASMODIUM FALCIPARUM</i>

2024-11-26

Abstract excerpt

<h4>ABSTRACT</h4> The mitochondrion of the deadliest human malaria parasite, Plasmodium falciparum, is an essential source of cellular acetyl-CoA during the asexual blood-stage of the parasite life cycle. Blocking mitochondrial acetyl-CoA synthesis leads to a hypoacetylated proteome and parasite death. We previously determined that mitochondrial acetyl-CoA is primarily synthesized from glucose-derived pyruvate b...

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Literature Corpus work: 0d818962-af15-5b64-87a4-d92753f5ff27
DOI: 10.1101/2024.11.26.624872

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MULTIPLE, REDUNDANT CARBOXYLIC ACID TRANSPORTERS SUPPORT MITOCHONDRIAL METABOLISM IN <i>PLASMODIUM FALCIPARUM</i>DOI 10.1101/2024.11.26.624872Read

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