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The metabolic repair enzyme phosphoglycolate phosphatase regulates central carbon metabolism and fosmidomycin sensitivity in <i>Plasmodium falciparum</i>

2018-09-12

Abstract excerpt

The asexual blood stages of the malaria parasite, Plasmodium falciparum are highly dependent on glycolysis for ATP synthesis, redox balance and provision of essential anabolic precursors. Recent studies have suggested that members of the haloacid dehalogenase (HAD) family of metabolite phosphatases may play an important role in regulating multiple pathways in P. falciparum central carbon metabolism. Here, we sho...

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Literature Corpus work
832e3df3-6b4d-5a74-9699-8cdbfa8ae7ba
DOI
10.1101/415505
Open publication

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