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Article

<i>EIF4EBP1</i> is transcriptionally upregulated by MYCN and associates with poor prognosis in neuroblastoma

2021-12-09

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Neuroblastoma (NB) accounts for 15% of cancer-related deaths in childhood despite considerable therapeutic improvements. While several risk factors, including MYCN amplification and alterations in RAS and p53 pathway genes, have been defined in NB, the clinical outcome is very variable and difficult to predict. Since genes of the mTOR pathway are up-regulated in MYCN -ampl...

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Literature Corpus work
0d778b6f-da73-5dd0-95dd-7385fde7d40d
DOI
10.1101/2021.12.08.471784
Open publication

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<i>EIF4EBP1</i> is transcriptionally upregulated by MYCN and associates with poor prognosis in neuroblastomaDOI 10.1101/2021.12.08.471784
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