Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Immunohistochemical analysis of PDK1, PHD3 and HIF-1α expression defines the hypoxic status of neuroblastoma tumors

8 Nov 2017

Abstract excerpt

Neuroblastoma (NB) is the most common solid tumor during infancy and the first cause of death among the preschool age diseases. The availability of several NB genomic profiles improves the prognostic ability, but the outcome prediction for this pathology remains imperfect. We previously produced a novel prognostic gene signature based on the response of NB cells to hypoxia, a condition of tumor microenvironment...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adrenal and Paraganglionic Tumors
Share to Cancer, Hypoxia, and Metabolism
Share to Neuroblastoma Research and Treatments

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29117193
DOI: 10.1371/journal.pone.0187206

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Immunohistochemical analysis of PDK1, PHD3 and HIF-1α expression defines the hypoxic status of neuroblastoma tumorsPMID 29117193Read ↗

Hypoxia Predicts Poor Prognosis in Neuroblastoma Patients and Associates with Biological Mechanisms Involved in Telomerase Activation and Tumor Microenvironment ReprogrammingSemantic proximity Read ↗

Integrative genomics reveals hypoxia inducible genes that are associated with a poor prognosis in neuroblastoma patientsSemantic proximity Read ↗

Molecular targeting therapies for neuroblastoma: Progress and challengesSemantic proximity Read ↗

Comprehensive Analysis Between Ferroptosis-Related Gene Signatures and Neuroblastoma PrognosisSemantic proximity Read ↗

Hypoxia and hypoxia-inducible factors in neuroblastomaSemantic proximity Read ↗

Construction of a ferroptosis-based prediction model for the prognosis of MYCN-amplified neuroblastoma and screening and verification of target sitesSemantic proximity Read ↗

A biology-driven approach identifies the hypoxia gene signature as a predictor of the outcome of neuroblastoma patientsSemantic proximity Read ↗

FUBP1 promotes neuroblastoma proliferation via enhancing glycolysis-a new possible marker of malignancy for neuroblastomaSemantic proximity Read ↗

Revolutionizing pediatric neuroblastoma treatment: unraveling new molecular targets for precision interventionsSemantic proximity Read ↗

The Neuroblastoma Microenvironment, Heterogeneity and Immunotherapeutic ApproachesSemantic proximity Read ↗

Identification of HBA2 and NR4A2 as potential prognostic molecular markers of MYCN amplified neuroblastomaSemantic proximity Read ↗

Neuroblastoma therapy: what is in the pipeline?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.