Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

RNA N6-methyladenosine reader IGF2BP3 interacts with MYCN and facilitates neuroblastoma cell proliferation

8 May 2023

Abstract excerpt

Neuroblastoma (NB) is a kind of typical life-threatening extracranial tumor in children. N6-methyladenosine (m6A) modification is closely related to multiple cancer pathological processes. Insulin-like growth factor 2 mRNA binding protein 3 (IGF2BP3) is a top-ranked prognostic risk gene in NB; however, its function is uncertain. The expression of m6A-associated enzymes in patients with NB was analyzed using the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer, Hypoxia, and Metabolism
Share to Neuroblastoma Research and Treatments
Share to RNA modifications and cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37156775
DOI: 10.1038/s41420-023-01449-3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

RNA N6-methyladenosine reader IGF2BP3 interacts with MYCN and facilitates neuroblastoma cell proliferationPMID 37156775Read ↗

m6A reader YTHDF1 inhibits the growth of neuroblastoma in vitro and in vivoSemantic proximity Read ↗

RNA N6-methyladenosine modification is required for miR-98/MYCN axis-mediated inhibition of neuroblastoma progressionSemantic proximity Read ↗

RNA N6-methyladenosine Reader IGF2BP2 Promotes Lymphatic Metastasis and Epithelial-mesenchymal Transition of Head and Neck Squamous Carcinoma Cells via Stabilizing Slug mRNA in an M6A-dependent MannerSemantic proximity Read ↗

Multi-omics analysis of N6-methyladenosine reader IGF2BP3 as a promising biomarker in pan-cancerSemantic proximity Read ↗

METTL14 promotes neuroblastoma by inhibiting YWHAH via an m6A-YTHDF1-dependent mechanismSemantic proximity Read ↗

A Pan-Cancer Analysis of the Oncogenic Role of Insulin-Like Growth Factor2 mRNA -Binding Protein 2 (IGF2BP2) in Human TumorsSemantic proximity Read ↗

The RNA N6 -methyladenosine modulator HNRNPA2B1 is involved in the development of non-small cell lung cancer.Semantic proximity Read ↗

The m6A reader IGF2BP3 Facilitates Gastric Cancer Progression Through Activating EMT via Upregulating MYC mRNA StabilitySemantic proximity Read ↗

Identification and Characterization of a Glucometabolic Prognostic Gene Signature in Neuroblastoma based on N6-methyladenosine Eraser ALKBH5Semantic proximity Read ↗

Comprehensive Analysis and Validation Reveal Potential MYCN Regulatory Biomarkers Associated with Prognosis of NeuroblastomaSemantic proximity Read ↗

Main N6-Methyladenosine Readers: YTH Family Proteins in CancersSemantic proximity Read ↗

The PLAGL2/MYCN/miR-506-3p interplay regulates neuroblastoma cell fate and associates with neuroblastoma progressionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.