Article

Impaired Barrier Integrity of the Skeletal Muscle Vascular Endothelium Drives Progression of Cancer Cachexia

2022-12-14

Abstract excerpt

Cancer patients experience cachexia, which is characterized by extensive skeletal muscle wasting that worsens the quality of life and increases mortality. Currently, there are no approved treatments that can effectively counteract cancer cachexia. Vascular endothelial cells (ECs) are essential for maintaining tissue perfusion, nutrient supply, and preventing inappropriate transmigration of immune cells into the ti...

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Literature Corpus work: 0d65ee2c-6cb8-5be8-bc4b-fb8d41f8ce07
DOI: 10.1101/2022.12.12.520118

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