Article

snpAD: An ancient DNA genotype caller

2018-03-24

Abstract excerpt

<h4>Motivation</h4> The study of ancient genomes can elucidate the evolutionary past. However, analyses are complicated by base-modifications in ancient DNA molecules that result in errors in DNA sequences. These errors are particularly common near the ends of sequences and pose a challenge for genotype calling. <h4>Results</h4> I describe an expectation-maximization algorithm that estimates genotype frequencies...

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Literature Corpus work: 0d48eebc-5d94-518e-ae27-f0fa6560e844
DOI: 10.1101/288258

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