Article
snpAD: an ancient DNA genotype caller.
Bioinformatics (Oxford, England) - 15 Dec 2018
Prüfer Kay
Abstract excerpt
Motivation: The study of ancient genomes can elucidate the evolutionary past. However, analyses are complicated by base-modifications in ancient DNA molecules that result in errors in DNA sequences. These errors are particularly common near the ends of sequences and pose a challenge for genotype calling. Results: I describe an iterative method that estimates genotype frequencies and errors along sequences to...
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