Article

Bradykinin Measurement by LC-MS/MS in Hereditary Angioedema Subjects Enhanced by Cold Activation

2024-12-26

Abstract excerpt

<h4>Background</h4> Bradykinin (BK) is a key mediator responsible for swelling episodes in hereditary angioedema due to C1INH deficiency/dysfunction (HAE-C1INH). Current BK measurement faces many challenges primarily related to very low levels and instability, and is not feasible for application in clinical settings. <h4>Objective</h4> This study aimed to develop a novel method to overcome the issues in current pr...

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Literature Corpus work: 0d1c291f-1d23-5679-8eab-540049d16853
DOI: 10.1101/2024.12.23.24319547

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