Article
Hereditary angioedema.
Journal of drugs in dermatology : JDD - 1 Oct 2006
Sachse Michael M, Khachemoune Amor, Guldbakke Kjetil K, Kirschfink Michael
Abstract excerpt
Hereditary angioedema (HAE) is a rare autosomal dominant disorder caused by a C1-inhibitor deficiency. It is characterized by potentially life-threatening recurrent episodes of angioedema of the skin and mucosa. Several recent studies have further elucidated the immunology of HAE implicating bradykinin, the key mediator of the contact system. This article reviews the pathophysiology, subtypes, and clinical...
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