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Article

Hereditary angioedema: the plasma contact system out of control.

Journal of thrombosis and haemostasis : JTH - 1 Sept 2018

De Maat S, Hofman Z L M, Maas C

Abstract excerpt

The plasma contact system contributes to thrombosis in experimental models. Even though our standard blood coagulation tests are prolonged when plasma lacks contact factors, this enzyme system appears to have a minor (if any) role in hemostasis. In this review, we explore the clinical phenotype of C1 esterase inhibitor (C1-INH) deficiency. C1-INH is the key plasma inhibitor of the contact system enzymes, and its...

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Share to Angioedemas, Hereditary
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 29920929
DOI: 10.1111/jth.14209

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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