Article

Type II diabetes may affect stem cell niche resulting in down regulation of glucose transporters and insulin receptors in cells

2018-07-06

Abstract excerpt

Characterized by high blood glucose concentration, resistance of cells to glucose uptake and reduced insulin sensitivity, Type II diabetes is a major health problem afflicting both developing and developed countries in increasing extent as populations around the world increasing adopt high energy diets. Given that, in Type II diabetes, successive generations of various cell types in the body ranging from muscles,...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 0d1bcb28-b748-583e-9273-865ae547a0d9
DOI: 10.7287/peerj.preprints.27024v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Type II diabetes may affect stem cell niche resulting in down regulation of glucose transporters and insulin receptors in cellsDOI 10.7287/peerj.preprints.27024v1Read

Diabetes treatment: A rapid review of the current and future scope of stem cell researchSemantic proximity Read

Type 2 diabetes across generations: from pathophysiology to prevention and management.Semantic proximity Read

The Landscape of microRNAs in βCell: Between Phenotype Maintenance and Protection.Semantic proximity Read

Stem-cell based organ-on-a-chip models for diabetes researchSemantic proximity Read

Stem cells as a therapeutic target for diabetesSemantic proximity Read

Understanding Genetic Heterogeneity in Type 2 Diabetes by Delineating Physiological Phenotypes: SIRT1 and its Gene Network in Impaired Insulin Secretion.Semantic proximity Read

Oxidative stress-mediated beta cell death and dysfunction as a target for diabetes managementSemantic proximity Read

Posttransplantation diabetes mellitus (PTDM): pharmacological aspects and genetic predispositions.Semantic proximity Read

Pancreatic β-cell failure, clinical implications, and therapeutic strategies in type 2 diabetesSemantic proximity Read

Insulin Resistance in Diabetes: The Promise of Using Induced Pluripotent Stem Cell TechnologySemantic proximity Read

Epigenetic Modifications Associated with the Pathogenesis of Type 2 Diabetes MellitusSemantic proximity Read

Pancreatic β-Cells and Type 2 Diabetes DevelopmentSemantic proximity Read