Article

Insulin Resistance in Diabetes: The Promise of Using Induced Pluripotent Stem Cell Technology

2020-02-07

Abstract excerpt

In this review, we discuss the insulin resistance (IR) and its development in the insulin target tissues that leads to diabetes. Also, we highlight the use of induced pluripotent stem cells (iPSCs) to understand the mechanisms underlying the development of IR. IR is associated with several metabolic disorders, including type 2 diabetes (T2D). The development of IR in insulin target tissues involves genetic and acq...

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Literature Corpus work: f6b12c86-254a-5c6d-aed0-45a1615aa374
DOI: 10.20944/preprints202002.0098.v1

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