Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Type 2 diabetes across generations: from pathophysiology to prevention and management.

Lancet (London, England) - 9 Jul 2011

Nolan Christopher J, Damm Peter, Prentki Marc

Abstract excerpt

Type 2 diabetes is now a pandemic and shows no signs of abatement. In this Seminar we review the pathophysiology of this disorder, with particular attention to epidemiology, genetics, epigenetics, and molecular cell biology. Evidence is emerging that a substantial part of diabetes susceptibility is acquired early in life, probably owing to fetal or neonatal programming via epigenetic phenomena. Maternal and early...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Diabetes, Gestational
Share to Diabetic Retinopathy
Share to Fetal Development

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Glucagon

Share to Glucagon-Like Peptide 1

Share to Insulin-Secreting Cells

Share to Life Style

Share to Prediabetic State

Source

Identifiers

PMID: 21705072
DOI: 10.1016/S0140-6736(11)60614-4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Type 2 diabetes across generations: from pathophysiology to prevention and management.PMID 21705072Read ↗

Pathogenesis of type 2 diabetes mellitus.Semantic proximity Read ↗

[Type 2 diabetes: journey in the heart of a complex disease].Semantic proximity Read ↗

Type 5 Diabetes Mellitus: Pathophysiology, Clinical Phenotype, and Nutritional Management.Semantic proximity Read ↗

Genetic underpinnnings of type 2 diabetes.Semantic proximity Read ↗

[Type 2 diabetes--a heterogeneous disease with a foetal predisposition].Semantic proximity Read ↗

Diabetes mellitus: The epidemic of the centurySemantic proximity Read ↗

Maternal diabetes, programming of beta-cell disorders and intergenerational risk of type 2 diabetes.Semantic proximity Read ↗

Unveiling Diabetes: Categories, Genetics, Diagnostics, Treatments, and Future Horizons.Semantic proximity Read ↗

Pathophysiology and treatment of type 2 diabetes: perspectives on the past, present, and future.Semantic proximity Read ↗

Lifetime Exposure Model of Type 2 DiabetesSemantic proximity Read ↗

Genetics of diabetes--are we missing the genes or the disease?Semantic proximity Read ↗

Genetic determinants and molecular pathways in the pathogenesis of Type 2 diabetes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.