Article

Morphological profiling of human T and NK lymphocytes identifies actin-mediated control of the immunological synapse

2020-01-17

Abstract excerpt

The detection and neutralization of infected cells and tumors by cytotoxic lymphocytes is a vital immune defense mechanism. The immunological synapse orchestrates the target recognition process and the subsequent cytotoxic activity. Here, we present an integrated experimental and computational strategy to systematically characterize the morphological properties of the immunological synapse of human cytotoxic lymph...

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Literature Corpus work: 0ceb1dba-263d-526d-9ea8-47e2cf1ce4a1
DOI: 10.1101/2020.01.17.910091

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