Article

scifAI: Explainable machine learning for profiling the immunological synapse and functional characterization of therapeutic antibodies

2022-10-25

Abstract excerpt

Therapeutic antibodies are widely used to treat severe diseases. Most of them alter immune cells and act within the immunological synapse; an essential cell-to-cell interaction to direct the humoral immune response. Although many antibody designs are generated and evaluated, a high-throughput tool for systematic antibody characterization and prediction of function is lacking. Here, we introduce the first comprehen...

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Literature Corpus work: 1e49ed7d-2a12-5a7e-b569-687459da5717
DOI: 10.1101/2022.10.24.513494

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