Article

scifAI: Explainable machine learning for profiling the immunological synapse and functional characterization of therapeutic antibodies

2022-11-09

Abstract excerpt

<title>Abstract</title> <p>Therapeutic antibodies are widely used to treat severe diseases. Most of them alter immune cells and act within the immunological synapse; an essential cell-to-cell interaction to direct the humoral immune response. Although many antibody designs are generated and evaluated, a high-throughput tool for systematic antibody characterization and prediction of function is lacking. Here, we i...

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Literature Corpus work: e440ea63-e2c5-5a5f-b71f-692226b430eb
DOI: 10.21203/rs.3.rs-2190942/v1

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