Article

Whole-exome sequencing analysis of mutation characteristics in recurrent or metastatic gastrointestinal stromal tumors

2022-04-18

Abstract excerpt

<h4>Purpose: </h4> Surgical resection for the metastasis and recurrence of gastrointestinal stromal tumors (GISTs) is controversial. Therefore, it is increasingly important to identify clinical factors related to survival and explore the driver genes and mutations in GIST. Patients and Methods: GIST patients who received two surgeries for primary and recurrent and/or metastatic tumors between January 2003 and Dece...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 0cb30370-0c3c-5573-9490-35ddc5efb6d9
DOI: 10.21203/rs.3.rs-1549241/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Whole-exome sequencing analysis of mutation characteristics in recurrent or metastatic gastrointestinal stromal tumorsDOI 10.21203/rs.3.rs-1549241/v1Read

Whole-exome Sequencing Analysis for Mutations Characteristics in Recurrent or Metastatic Gastrointestinal Stromal TumorsSemantic proximity Read

Molecular characteristics and metastatic mechanism of patients diagnosed with Krukenberg tumor from gastric cancerSemantic proximity Read

Genetic alterations and their clinical implications in gastric cancer peritoneal carcinomatosis revealed by whole-exome sequencing of malignant ascites.Semantic proximity Read

Multiomic Landscape of Gastrointestinal Stromal Tumors in a Real-World Patient Cohort of 1,427 Cases.Semantic proximity Read

Correlation of Long-term Results of Imatinib in Advanced Gastrointestinal Stromal Tumors With Next-Generation Sequencing Results: Analysis of Phase 3 SWOG Intergroup Trial S0033.Semantic proximity Read

Genomic aberrations in cell cycle genes predict progression of KIT-mutant gastrointestinal stromal tumors (GISTs)Semantic proximity Read

KIT mutations and expression: current knowledge and new insights for overcoming IM resistance in GIST.Semantic proximity Read

Molecular characterization of metastatic exon 11 mutant gastrointestinal stromal tumors (GIST) beyond KIT/PDGFRα genotype evaluated by next generation sequencing (NGS).Semantic proximity Read

Genomic and transcriptomic landscape of human gastrointestinal stromal tumors.Semantic proximity Read

Molecular Features of Gastrointestinal Stromal Tumors: A Single Referral Cancer Center Experience.Semantic proximity Read

Current management of gastrointestinal stromal tumors: Surgery, current biomarkers, mutations, and therapy.Semantic proximity Read

Genomic landscape and mutational impacts of recurrently mutated genes in cancers.Semantic proximity Read