Article

Functional characterisation of a HOX/PBX transcriptional complex

1998-01-01

Abstract excerpt

Hox genes control cell fates and specify regional identities during vertebrate development. Hox proteins relaxed DNA-binding selectivity in vitro, suggests that Hox specificity of action is achieved in vivo through the action of transcriptional cofactors. Members of the EXD/PBX family of homeoproteins have been proposed for such a role on the basis of genetic and biochemical evidence. In this work we show that the...

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Literature Corpus work: 0cafe00e-1198-536e-adb9-4f793714d567
DOI: 10.21954/ou.ro.0000e192

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