Article
Sequences outside the homeodomain of bicoid are required for protein-protein interaction.
The Journal of biological chemistry - 30 Aug 1996
Yuan D, Ma X, Ma J
Abstract excerpt
The Drosophila morphogenetic protein Bicoid (Bcd) is required for the development of anterior structures of the embryo. Bcd, a homeodomain protein, is distributed as an anterior-to-posterior gradient in the embryo. It stimulates the expression of the hunchback (hb) gene in the anterior half in an all-or-none fashion. We have recently shown that Bcd binds cooperatively to a hb enhancer element and proposed that...
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