Article
Definition of the transcriptional activation domains of three human HOX proteins depends on the DNA-binding context.
Molecular and cellular biology - 1 Nov 1998
Viganò M A, Di Rocco G, Zappavigna V, Mavilio F
Abstract excerpt
Hox proteins control developmental patterns and cell differentiation in vertebrates by acting as positive or negative regulators of still unidentified downstream target genes. The homeodomain and other small accessory sequences encode the DNA-protein and protein-protein interaction functions whic...
Topics
- Amino Acid Sequence
- Animals
- Cell Line
- DNA-Binding Proteins
- Genes, Reporter
- Homeodomain Proteins
- Humans
- Molecular Sequence Data
- Mutation
- Neoplasm Proteins
- Recombinant Fusion Proteins
- Saccharomyces cerevisiae Proteins
- Sequence Homology, Nucleic Acid
- Transcription Factors
- Transcriptional Activation
- Transfection
- Xenopus Proteins