Article

Intrinsic excitability controls structural plasticity of cerebellar climbing fibers

2025-11-25

Abstract excerpt

<h4>ABSTRACT</h4> In the cerebellum, climbing fibers (CFs) convey a teaching signal to Purkinje cells (PCs) that is crucial for cerebellar learning. They undergo activity-dependent synaptic plasticity during development and learning, and their transverse branches have an activity-dependent control of mobility. The maintenance of their structure was shown to rely on the growth-associated protein 43 (GAP-43), which...

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Literature Corpus work: 0c965dff-135c-5c5c-9d3c-98ee65f0ad26
DOI: 10.1101/2025.11.24.690115

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