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Close relatives of MERS-CoV in bats use ACE2 as their functional receptors

2022-01-25

Abstract excerpt

<h4>Summary</h4> Middle East Respiratory Syndrome coronavirus (MERS-CoV) and several bat coronaviruses employ Dipeptidyl peptidase-4 (DPP4) as their functional receptors 1–4 . However, the receptor for NeoCoV, the closest MERS-CoV relative yet discovered in bats, remains enigmatic 5 . In this study, we unexpectedly found that NeoCoV and its close relative, PDF-2180-CoV, can efficiently use some types of bat Ang...

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Literature Corpus work
0c8ea56f-f201-5e2e-9a80-a1d6007982a1
DOI
10.1101/2022.01.24.477490
Open publication

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Close relatives of MERS-CoV in bats use ACE2 as their functional receptorsDOI 10.1101/2022.01.24.477490
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