Article
Heteroresistance at the single-cell level: adapting to antibiotic stress through a population-based strategy and growth-controlled interphenotypic coordination.
mBio - 11 Feb 2014
Wang Xiaorong, Kang Yu, Luo Chunxiong, Zhao Tong, Liu Lin, Jiang Xiangdan, Fu Rongrong, An Shuchang, Chen Jichao, Jiang Ning, Ren Lufeng, Wang Qi, Baillie J Kenneth, Gao Zhancheng, Yu Jun
Abstract excerpt
UNLABELLED: Heteroresistance refers to phenotypic heterogeneity of microbial clonal populations under antibiotic stress, and it has been thought to be an allocation of a subset of "resistant" cells for surviving in higher concentrations of antibiotic. The assumption fits the so-called bet-hedging...
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