Article

The Effects of Lamin B Receptor knockdown on a Myeloid Leukemia Cell

2024-06-20

Abstract excerpt

In an effort to extend our understanding of the genetic functions of the nuclear envelope protein Lamin B Receptor (LBR), we examined the effect of a stable short hairpin (sh1) RNAi knockdown of LBR on the transcriptome and immunostained morphology of the human myeloid leukemia cell line (HL-60/S4). This examination was on sh1 cells induced to granulocytic form with Retinoic Acid (RA) versus sh1 cells maintained u...

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Literature Corpus work: 0c20e38d-315c-5c16-bdb3-01d841466d53
DOI: 10.1101/2024.06.19.598074

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