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Article

Ribosomal proteins sustain morphology, function and phenotype in acute myeloid leukemia blasts.

Leukemia research - 1 Apr 1998

Bassøe C F, Bruserud O, Pryme I F, Vedeler A

Abstract excerpt

Translation of mRNA is a prerequisite for cell proliferation, differentiation and viability. We have studied the effect of ribosome protein factors (GPRE) on acute myeloid leukemia (AML) blast cells. Ribosomes were isolated from MPC-11 cells using ultra-centrifugation. GPRE were extracted using a high KCl procedure. Blast cells from six AML patients were grown in suspension cultures for 24 and 96 h. GPRE or...

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PMID: 9669838
DOI: 10.1016/s0145-2126(97)00178-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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