Ribosomal proteins sustain morphology, function and phenotype in acute myeloid leukemia blasts.

doi:10.1016/s0145-2126(97)00178-1

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Article

Ribosomal proteins sustain morphology, function and phenotype in acute myeloid leukemia blasts.

Leukemia research - 1 Apr 1998

Bassøe C F, Bruserud O, Pryme I F, Vedeler A

Abstract excerpt

Translation of mRNA is a prerequisite for cell proliferation, differentiation and viability. We have studied the effect of ribosome protein factors (GPRE) on acute myeloid leukemia (AML) blast cells. Ribosomes were isolated from MPC-11 cells using ultra-centrifugation. GPRE were extracted using a...

Topics

Acute Disease
Adult
Aged
Aged, 80 and over
Cell Membrane
Cell Survival
DNA
Female
Histocytochemistry
Humans
Integrin alphaXbeta2
Leukemia, Myeloid
Leukocytes, Mononuclear
Light
Macrophage-1 Antigen
Male
Middle Aged
Phagocytosis

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