Article

HER2 G776S Mutation Promotes Oncogenic Potential in Colorectal Cancer Cells when Accompanied by Loss of APC Function

2021-06-15

Abstract excerpt

<title>Abstract</title> <p>Background Clinical cancer genome sequencing detects oncogenic variants that are potential targets for cancer treatment, but it also detects variants of unknown significance that may interact and affect the pathophysiology of the tumor; however, these interactions are not fully understood. In this study, we examined the interactions of a minor <italic>HER2</italic> mutation (G776S) and...

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Literature Corpus work: 0bf603a3-19ad-512d-ae04-b6bbc0b1eba5
DOI: 10.21203/rs.3.rs-594302/v1

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