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Article

Cancer genetics: tumor suppressor meets oncogene.

Current biology : CB - 28 Jan 1999

Fearon E R, Dang C V

Abstract excerpt

The adenomatous polyposis coli (APC) tumor suppressor protein is inactivated by mutations in the majority of colorectal cancers. A recent study has revealed that alterations in the APC signaling pathway can result in the transcriptional activation of the c-MYC gene.

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Topics

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Share to APC gene
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Share to Genes, APC
Share to Genes, myc

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 10021355
DOI: 10.1016/s0960-9822(99)80012-8

Genes

APC
MYC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Interactions and functions of the adenomatous polyposis coli (APC) protein at a glance.Semantic proximity Read ↗

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