Article

Molecular Structure and Enzymatic Mechanism of the Human Collagen Hydroxylysine Galactosyltransferase GLT25D1/COLGALT1

2024-06-22

Abstract excerpt

<h4>ABSTRACT</h4> During biosynthesis, collagen lysine residues undergo extensive post-translational modifications essential for the stability and functions of collagen supramolecular assemblies. In the endoplasmic reticulum, two distinct metal ion dependent enzyme families (i.e., multifunctional lysyl hydroxylases-glucosyltransferases LH/PLODs and galactosyltransferases GLT25D/COLGALT) alternatively operate on c...

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Literature Corpus work: 0bcfedc4-2a7f-5ccc-99bb-ca8a0ee230ad
DOI: 10.1101/2024.06.21.600124

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