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Article

Role of Glycosyltransferase 25 Domain 1 in Type I Collagen Glycosylation and Molecular Phenotypes.

Biochemistry - 17 Dec 2019

Terajima Masahiko, Taga Yuki, Sricholpech Marnisa, Kayashima Yukako, Sumida Noriko, Maeda Nobuyo, Hattori Shunji, Yamauchi Mitsuo

Abstract excerpt

Glycosylation in type I collagen occurs as O-linked galactosyl- (G-) lesser and glucosylgalactosyl-hydroxylysine (GG-Hyl); however, its biological significance is still not well understood. To investigate the function of this modification in bone, we have generated preosteoblast MC3T3-E1 (MC)-derived clones, short hairpin (Sh) clones, in which Glt25d1 gene expression was stably suppressed. In Sh clones, the...

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Identifiers

PMID: 31726007
DOI: 10.1021/acs.biochem.8b00984
PMCID: PMC7887705

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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