Article
Tunable T cell immunity towards a protein antigen using polymersomes vs. solid-core nanoparticles.
Biomaterials - 1 Jun 2013
Stano Armando, Scott Evan A, Dane Karen Y, Swartz Melody A, Hubbell Jeffrey A
Abstract excerpt
Using poly(propylene sulfide) (PPS) and poly(ethylene glycol) (PEG) as components of a nanocarrier platform, we sought to compare immune responses induced by PPS-bl-PEG polymersomes (PSs; watery-core structures, with antigen incorporated within the PSs) and PEG-stabilized PPS nanoparticles (NPs; solid-core structures, with antigen conjugated upon the NP surface). We have previously shown strong CD8(+) T cell...
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