Integrating immunophenotypes reveals causal relationship between tuberculosis and lung cancer: Mendelian randomization study

Abstract excerpt

<h4>Background</h4> Tuberculosis (TB) and lung cancer (LC) are major respiratory diseases causing significant deaths worldwide. Both primarily affect the lungs and share similar clinical symptoms. The comorbidity rate between TB and LC is high, and epidemiological data suggest a potential association between the two diseases. However, the detailed causal relationships and potential mediators remain underexplored d...

Topics

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• Adenocarcinoma of Lung
• Carcinoma, Non-Small-Cell Lung
• Genetic Predisposition to Disease
• Genome-Wide Association Study
• Lung Neoplasms
• Mendelian Randomization Analysis
• Polymorphism, Single Nucleotide
• Small Cell Lung Carcinoma

Identifiers and source

Literature Corpus work

0b82f064-3da6-5189-b358-53d4b11b0a5e

DOI

10.1101/2024.06.10.24308725