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Article

Causal association between immune cells and lung cancer risk: a two-sample bidirectional Mendelian randomization analysis.

Frontiers in immunology - 1 Jan 2024

Xu Shengshan, Fang Huiying, Shen Tao, Zhou Yufu, Zhang Dongxi, Ke Yongwen, Chen Zhuowen, Lu Zhuming

Abstract excerpt

Background: Previous studies have highlighted the crucial role of immune cells in lung cancer development; however, the direct link between immunophenotypes and lung cancer remains underexplored. Methods: We applied two-sample Mendelian randomization (MR) analysis, using genetic variants as instruments to determine the causal influence of exposures on outcomes. This method, unlike traditional randomized...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 38962009
DOI: 10.3389/fimmu.2024.1433299
PMCID: PMC11219561

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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