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Article

Causal effect of immune cells on idiopathic pulmonary fibrosis: A mendelian randomization study.

Heart & lung : the journal of critical care - 1 Jan 2024

Li Xuannian, Zhou Bowen, Xu Fei, Liu Huaman, Jia Xinhua

Abstract excerpt

BACKGROUND: A key component of idiopathic pulmonary fibrosis (IPF) is the involvement of immune cells. However, the causal interaction between different immune cell signatures and IPF remain inconclusive. OBJECTIVES: Based on publicly accessible data, our study utilized the Mendelian randomization (MR) approach to determine the causative relevance of complex immune cell phenotypes in IPF. METHODS: We deployed a...

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Genetic Predisposition to Disease
Genome-Wide Association Study
Idiopathic Pulmonary Fibrosis
Mendelian Randomization Analysis
Polymorphism, Single Nucleotide

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 38865855
DOI: 10.1016/j.hrtlng.2024.06.003

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