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Article

The causal role of immune cells on lung cancer: a bi-directional Mendelian randomization (MR) study.

Aging - 12 Jun 2024

Zhu Hongyu, Chen Caihua, Guo Haixie, Zhang Bo, Hu Quanteng

Abstract excerpt

Immune cells play a vital role in the development and progression of lung cancer (LC). We aimed to explore the causal role of immune cells in LC with Mendelian randomization (MR) study. Summary statistic data used in the study were obtained from genome-wide association studies (GWAS). A comprehensive two-sample MR was carried out to explore the causal role of 731 immune cell traits (ICTs) in LC, Non-small cell...

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Carcinoma, Non-Small-Cell Lung
Genetic Predisposition to Disease
Genome-Wide Association Study
Lung Neoplasms
Mendelian Randomization Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

Small Cell Lung Carcinoma

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Identifiers

PMID: 38870262
DOI: 10.18632/aging.205917
PMCID: PMC11210237

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