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Article

Causal Involvement of Immune Cells in Chronic Obstructive Pulmonary Disease: A Mendelian Randomization Study.

International journal of chronic obstructive pulmonary disease - 1 Jan 2024

Guan Tiefa, Qin Yibing, Qu Nini, Pan Yushuo

Abstract excerpt

Background: The immune cells play a substantial role in the development and progression of chronic obstructive pulmonary disease (COPD). We aim to investigate the causal involvement of immune cells in COPD via a Mendelian randomization (MR) analysis. Methods: Published genome-wide association studies (GWAS) statistics on immune cells were analyzed, with genetic variants identified as instrumental variables (IVs)....

Topics

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Dendritic Cells
Genome-Wide Association Study
Killer Cells, Natural
Lung
Mendelian Randomization Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Pulmonary Disease, Chronic Obstructive

Risk Assessment

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Open in PubMed Open full text

Identifiers

PMID: 39011122
DOI: 10.2147/COPD.S460342
PMCID: PMC11247341

Genes

CCR2
CD19
CD24
CD28
CD38

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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