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Article

Streptozotocin mechanisms and its role in rodent models for Alzheimer’s disease

2022-12-05

Abstract excerpt

The majority of dementia is caused by Alzheimer’s disease (AD) that manifests in the familial and sporadic forms. The latter accounts for the most of the cases and is a complex multi-factorial disorder with no cure. Despite the vast growth of animal models, both the transgenic and non-transgenic therapeutic findings for AD seem ambiguous. Streptozotocin (STZ) administration is the most accepted sporadic rodent AD...

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Literature Corpus work
0b399bb4-83a5-514e-9cb9-acf650355a72
DOI
10.1080/15569543.2022.2150646
Open publication

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