Article

Antipsychotic drugs selectively decorrelate long-range interactions in deep cortical layers

2022-01-31

Abstract excerpt

Psychosis is characterized by a diminished ability of the brain to distinguish externally driven activity patterns from self-generated activity patterns. Antipsychotic drugs are a class of small molecules with relatively broad binding affinity for a variety of neuromodulator receptors that, in humans, can prevent or ameliorate psychosis. How these drugs influence the function of cortical circuits, and in particula...

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Literature Corpus work: 0b1325e0-7861-566f-af11-e47ca711a494
DOI: 10.1101/2022.01.31.478462

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