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Article

Aberrant Cortical Ensembles and Schizophrenia-like Sensory Phenotypes in Setd1a+/- Mice.

Biological psychiatry - 1 Aug 2020

Hamm Jordan P, Shymkiv Yuriy, Mukai Jun, Gogos Joseph A, Yuste Rafael

Abstract excerpt

BACKGROUND: A breakdown of synchrony within neuronal ensembles leading to destabilization of network "attractors" could be a defining aspect of neuropsychiatric diseases such as schizophrenia, representing a common downstream convergence point for the diverse etiological pathways associated with the disease. Using a mouse genetic model, we demonstrated that altered ensembles are associated with pathological...

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Identifiers

PMID: 32143831
DOI: 10.1016/j.biopsych.2020.01.004
PMCID: PMC7363535

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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