Article

Spatially resolved multiomics of human cardiac niches

2023-02-01

Abstract excerpt

A cell’s function is defined by its intrinsic characteristics and its niche: the tissue microenvironment in which it dwells. Here, we combine single-cell and spatial transcriptomic data to discover cellular niches within eight regions of the human heart. We map cells to micro-anatomic locations and integrate knowledge-based and unsupervised structural annotations. For the first time, we profile the cells of the hu...

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Literature Corpus work: 0af99a4a-ac1a-599d-9f8d-f7bb2b89e96a
DOI: 10.1101/2023.01.30.526202

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