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Comprehensive analysis of scRNA-Seq and bulk RNA-Seq reveals the non-cardiomyocytes heterogeneity and novel cell populations in dilated cardiomyopathy

2024-10-22

Abstract excerpt

<title>Abstract</title> <p>Background Dilated cardiomyopathy (DCM) is one of the most common causes of heart failure. Infiltration and alterations in non-cardiomyocytes of the human heart involve crucially in the progression of DCM and associated immunotherapeutic approaches. Methods We constructed a single-cell transcriptional atlas of DCM and normal patients. Then, the xCell algorithm, EPIC algorithm, MCP cou...

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Literature Corpus work
e8bb6b05-aaed-548a-b064-1bb8d5158487
DOI
10.21203/rs.3.rs-4882557/v1
Open publication

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