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The signature of HBV-related liver disease in peripheral blood mononuclear cell DNA methylation

8 Jun 2020

Abstract excerpt

Abstract Background Hepatitis B virus (HBV)-related liver disease induces liver damage by hepatic immune and inflammatory response. The association between aberrant peripheral blood mononuclear cell (PBMC) DNA methylation and progression of liver disease and fibrosis remains unclear. Results Here we applied Infinium 450 K BeadChip investigating PBMC genome-wide methylation profiling of 48 HBV-related liver...

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Share to Epigenetics and DNA Methylation
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PMID: 32513305
DOI: 10.1186/s13148-020-00847-z

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