Article

GPER agonist G1 suppresses neuronal apoptosis mediated by endoplasmic reticulum stress after exertional heat stroke injury

2025-12-03

Abstract excerpt

<title>Abstract</title> <p>Exertional heat stroke (EHS) poses a significant public health challenge because of its elevated rates of mortality and disability. Sex differences in incidence have been noted, and estrogen may be a contributing factor. The innovative G protein-coupled estrogen receptor (GPER) is recognized for its protective function in various diseases via the rapid non-genomic pathway associated wit...

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Literature Corpus work: 0ac62698-0487-595a-bd95-00f00ac0450c
DOI: 10.21203/rs.3.rs-8100858/v1

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