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Article

CD44 Promotes Inflammation and Extracellular Matrix Production During Arteriovenous Fistula Maturation.

Arteriosclerosis, thrombosis, and vascular biology - 1 Jun 2017

Kuwahara Go, Hashimoto Takuya, Tsuneki Masayuki, Yamamoto Kota, Assi Roland, Foster Trenton R, Hanisch Jesse J, Bai Hualong, Hu Haidi, Protack Clinton D, Hall Michael R, Schardt John S, Jay Steven M, Madri Joseph A, Kodama Shohta, Dardik Alan

Abstract excerpt

OBJECTIVE: Arteriovenous fistulae (AVF) remain the optimal conduit for hemodialysis access but continue to demonstrate poor patency and poor rates of maturation. We hypothesized that CD44, a widely expressed cellular adhesion molecule that serves as a major receptor for extracellular matrix components, promotes wall thickening and extracellular matrix deposition during AVF maturation. APPROACH AND RESULTS: AVF...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28450292
DOI: 10.1161/ATVBAHA.117.309385
PMCID: PMC5467640

Genes

CD44

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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