Article

Emodin Protects SH-SY5Y Cells Against Zinc-Induced Synaptic Impairment and Oxidative Stress Through ERK1/2 Pathway

2021-08-24

Abstract excerpt

<h4>Background: </h4> Zinc is an essential trace element important for the physiological function of the central nervous system. The abnormal accumulation of zinc inside neurons may induce mitochondrial dysfunction and oxidative stress which contributes to many brain diseases. We hypothesized that natural anthraquinone derivative emodin can protect against neurotoxicity induced by pathological concentrations of zi...

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Literature Corpus work: 0a82fe8f-0fd8-5899-91b0-15fe1244735c
DOI: 10.21203/rs.3.rs-829075/v1

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