Article
The Multifaceted Roles of Zinc in Neuronal Mitochondrial Dysfunction
2021-03-02
Abstract excerpt
Zinc is a highly abundant cation in the brain, where it is essential for cellular function, including transcription, enzymatic activity, and cell signaling. However, zinc can also trigger injurious cascades in neurons, contributing to the pathology of neurodegenerative diseases. Mitochondria, critical for meeting the high energy demands of the central nervous system (CNS), are a principal target of the deleterious...
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Identifiers and source
- Literature Corpus work
- 2f4c00c8-0524-5eba-a0b8-4d75f7845de9
- DOI
- 10.20944/preprints202103.0043.v1