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Zinc oxide nanoparticles modulate the gene expression of ZnT <sub>1</sub> and ZIP <sub>8</sub> to manipulate zinc homeostasis and stress-induced cytotoxicity in human neuroblastoma SH-SY5Y cells

2020-04-22

Abstract excerpt

Zinc ions (Zn 2+ ) are important messenger molecules involved in various physiological functions. To maintain the homeostasis of cytosolic Zn 2+ concentration ([Zn 2+ ] c ), Zrt/Irt-related proteins (ZIPs) and Zn 2+ transporters (ZnTs) are the two families of proteins responsible for decreasing and increasing the [Zn 2+ ] c , respectively, by fluxing Zn 2+ across the membranes of the cell and intracellular...

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Literature Corpus work
a968b614-011e-5553-a880-20a33fc767ad
DOI
10.1101/2020.04.22.055152
Open publication

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Zinc oxide nanoparticles modulate the gene expression of ZnT <sub>1</sub> and ZIP <sub>8</sub> to manipulate zinc homeostasis and stress-induced cytotoxicity in human neuroblastoma SH-SY5Y cellsDOI 10.1101/2020.04.22.055152
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