Article
DE NOVO MUTATIONS IN AUTISM IMPLICATE THE SYNAPTIC ELIMINATION NETWORK.
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing - 1 Jan 2017
Venkataraman Guhan Ram, O'Connell Chloe, Egawa Fumiko, Kashef-Haghighi Dorna, Wall Dennis P
Abstract excerpt
Autism has been shown to have a major genetic risk component; the architecture of documented autism in families has been over and again shown to be passed down for generations. While inherited risk plays an important role in the autistic nature of children, de novo (germline) mutations have also been implicated in autism risk. Here we find that autism de novo variants verified and published in the literature are...
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